Rosuvastatin

HOW TO TAKE
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. 

• Take rosuvastatin once each day, exactly as your doctor tells you to. There are several strengths of tablet available, so your doctor will tell you which strength is right for you.
• You can take rosuvastatin at a time of day to suit you. You should, however, try to take your doses at the same time of day each day. 
• Swallow the tablet with a drink of water. You can take rosuvastatin before or after food.
• If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, miss out the forgotten dose. Do not take two doses at the same time to make up for a forgotten dose.
• Use this medicine only as directed by your doctor. Do not use more or less of it, and do not use it more often or for a longer time than your doctor ordered. Also, this medicine works best if there is a constant amount in the blood. To help keep this amount constant, do not miss any doses and take the medicine at the same time each day.
• Remember that this medicine will not cure your condition but it does help control it. Therefore, you must continue to take it as directed if you expect to keep your cholesterol levels down.
• Follow carefully the special diet your doctor gave you. This is the most important part of controlling your condition and is necessary if the medicine is to work properly.

DOSAGE AND ADMINISTRATION
Adult 
5-40 mg PO once daily, not to exceed 40 mg/day
Please check with your doctor or pharmacist which start dose of Rosuvastatin will suitable for you.
Your doctor may decide to give you the lowest dose if:

• You are over 70 years of age.
• You have moderate kidney problems.
• You are at risk of muscle aches and pains (Myopathy).

WARNING AND PRECAUTION
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking rosuvastatin it is important that your doctor knows:

• If you have ever had an allergic reaction to rosuvastatin, or to any of its ingredients.
• If you are pregnant or breast-feeding: Rosuvastatin should not be used during pregnancy or by women who plan to become pregnant.
• If you have liver disease.
• If you have severe kidney problems.
• If you have moderate kidney problems (if in doubt, please ask your doctor).
• If your thyroid gland is not working properly.
• If you have had any repeated or unexplained muscle aches or pains, a personal or family history of muscle problems, or a previous history of muscle problems when taking other cholesterol-lowering medicines.
• If you regularly drink large amounts of alcohol.
• If you take other medicines called fibrates to lower your cholesterol.
• If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.When you are taking rosuvastatin, it is especially important that your doctor and pharmacist know if you are taking any of the following: antacid, aluminum and magnesium hydroxide-containing, Cyclosporine, Gemfibrozil, niacin, Warfarin
• Protein in the urine-Rosuvastatin may cause this problem. Your doctor may want to decrease the dose of rosuvastatin if you get this problem.
• Major surgery or trauma, recent-Patients with these conditions may be at risk of developing muscle problems (causing the release of muscle pigment into the urine) that may lead to kidney failure
• Other medical problems: The presence of other medical problems may affect the use of rosuvastatin. Make sure you tell your doctor if you have any other medical problems.

PREGNANCY AND BREAST FEEDING
Do not take Rosuvastatin if you are pregnant or breast-feeding.

SIDE EFFECTS
All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; headache; nausea; stomach pain; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody or dark urine; change in the amount of urine produced; chest pain; confusion; depression; joint pain; memory problems (eg, forgetfulness, memory loss); muscle pain, tenderness, or weakness (with or without fever or fatigue); red, swollen, blistered, or peeling skin; severe or persistent headache; severe or persistent nausea or vomiting; severe stomach or back pain (with or without nausea or vomiting); swelling of the hands, ankles, or feet; symptoms of liver problems (eg, yellowing of the skin or eyes, dark urine, pale stools, loss of appetite, unusual tiredness); trouble sleeping.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency.

STORAGE

• Store Rosuvastatin below 30˚C.
• Store away from heat, moisture, and light.
• Keep out of the reach of children and away from pets.
• Store in the original package.
• Do not use Rosuvastatin after the expiry date which is stated on the label after EXP.